I think AC Content Manager is the best launcher for AC out there and have bought a key ...
However I use a projector on my rig that projects onto a curved screen, In order to get the projected image to display correct i have to use image warping software ... in my case i use Immersive Display Pro but there are many other screen warping software's available.
Unfortunately Screen Warping software can play havoc with non standard windows user interfaces especially if they use direct hardware acceleration as this by passes Windows desktop API and thus the screen warping software.
I've tried disabling the hardware UI acceleration in content manager by checking the box in Settings -> Appearance and restarting CM but the setting does not seem to stick on a restart of CM so reporting it as an bug/issue.
I also use Sim Commander which also has a custom GUI and use to suffer from exactly the same UI issues that effect CM, however a while ago they have added an option to disable hardware UI acceleration and now the GUI works perfect.
Hopefully once the issue is fixed in CM I can go back to using it but at the moment its pretty much unusable while its locked into HW UI acceleration.
PS: I also posted this bug on the AC - CM Forum :-